The Effect of Rosuvastatin on Low-Density Lipoprotein Subfractions in Patients With Impaired Fasting Glucose

Preamble of the study Statins are the cornerstone of hypercholesterolemia treatment Among statins, rosuvastatin is considered the most potent in beneficially modifying the serum lipid profile and altering LDL subfraction distribution On the other hand, statin treatment has been associated with the development of new-onset diabetes mellitus To date, it is unclear whether statin intervention… Continue reading The Effect of Rosuvastatin on Low-Density Lipoprotein Subfractions in Patients With Impaired Fasting Glucose

Bivalirudin versus heparin in patients planned for percutaneous coronary intervention: a meta-analysis of randomised controlled trials

Salient features of the study The authors searched Medline, the Cochrane Library, and relevant meeting abstracts (search done on April 9, 2014) for randomised trials that assessed bivalirudin versus heparin in patients planned for PCI Primary efficacy endpoint – ¬†incidence of major adverse cardiac events (MACE) up to 30 days Secondary efficacy endpoints – death,… Continue reading Bivalirudin versus heparin in patients planned for percutaneous coronary intervention: a meta-analysis of randomised controlled trials

Childhood 25-OH Vitamin D Levels and Carotid Intima-Media Thickness in Adulthood: The Cardiovascular Risk in Young Finns Study

Preamble There is increasing interest in the association between vitamin D and atherosclerotic disease Low levels of vitamin D have been shown to be related to increased risk of stroke, myocardial infarction (MI), and total cardiovascular events Increased carotid IMT is a marker of structural atherosclerosis, which correlates with cardiovascular risk factors, and predicts cardiovascular… Continue reading Childhood 25-OH Vitamin D Levels and Carotid Intima-Media Thickness in Adulthood: The Cardiovascular Risk in Young Finns Study

The Effect of Rosuvastatin on Low-Density Lipoprotein Subfractions in Patients With Impaired Fasting Glucose J Cardiovasc Pharmacol Ther published online 18 September 2014

Preamble of the study Statins are the cornerstone of hypercholesterolemia treatment Among statins, rosuvastatin is considered the most potent in beneficially modifying the serum lipid profile and altering LDL subfraction distribution On the other hand, statin treatment has been associated with the development of new-onset diabetes mellitus To date, it is unclear whether statin intervention… Continue reading The Effect of Rosuvastatin on Low-Density Lipoprotein Subfractions in Patients With Impaired Fasting Glucose J Cardiovasc Pharmacol Ther published online 18 September 2014

NACIAM trial: The early use of N-acetylcysteine (NAC) with glyceryl trinitrate (GTN) in ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention. European Society of Cardiology 2016 Congress; August 28, 2016; Rome, Italy. Abstract 2227

Preamble N-Acetylcysteine (NAC) is an anti-oxidant which potentiates the action of nitroglycerine When used with nitrates in the context of acute myocardial infarction, it may reduce infarct size by minimising reperfusion injury as well as potentiating nitroglycerine’s vasodilating and anti-platelet effects Salient Features The NACIAM trial – The early use of N-Acetyl Cysteine In Acute… Continue reading NACIAM trial: The early use of N-acetylcysteine (NAC) with glyceryl trinitrate (GTN) in ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention. European Society of Cardiology 2016 Congress; August 28, 2016; Rome, Italy. Abstract 2227

INTERSTROKE study

Read online at http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30506-2/abstract Objective: To¬† evaluate variations in common risk factors for stroke by major regions of the world, in key populations (eg, ethnic origin, age, sex), and in subtypes of stroke. Methods Participants were recruited from 2007-15, from 32 countries (including India) from different parts of world Following factors were evaluated for association… Continue reading INTERSTROKE study